Recently, the achievement "Basic Theory and Methods of Micro-nano Manipulation, Manufacturing and Testing for Bio-syncretic Robots" by Shenyang Institute of Automation (SIA), Chinese Academy of Sciences (CAS), won the first prize of Liaoning Provincial Natural Science Award.

The reserach of bio-syncretic robots is an emerging direction and hot spot in robot research and is a potential subversive method for the further development of robots. It is based on the deep integration of biological systems and electromechanical systems, directly utilizing living materials to realize robotic functions, such as sensing, intelligence and actuation. Due to the introduction of highly unstructured and unknown biological materials, research on bio-syncretic robots urgently needs new relevant technologies for manipulation, fabrication and detection.

In the project "Basic Theories and Methods of Micro-nano Manipulation, Manufacturing and Testing for Bio-syncretic Robots," researchers from SIA aimed at the key scientific and technical issues about bio-syncretic robots and carried out multiple original studies.

A super-resolution imaging system based on microspheres was developed, and the mechanism of evanescent wave super-resolution imaging was clarified. The super-resolution dynamic real-time observation and the coordinated nano-manipulation of cellular molecules in a physiological environment was realized. An optoelectronic tweezer manipulation system was developed, and the coupling relationship between cell membrane capacitance and manipulation force was revealed, which supported the nondestructive manipulation of cells and the fabrication and assembly of bio-syncretic systems. An active viscoelastic cell dynamic model based on subcellular structure was established, the modeling error caused by passive ideal linear elastic theory was effectively overcome, and various bio-syncretic actuation systems were constructed, which realized controllable motion based on living muscle cells.